When a protein sequence is added to the registry, the system searches an internal library for matching annotations. Matching annotations are automatically associated with the protein sequence and displayed in a viewer. Protein annotations can also be added manually, edited, and removed for a registered sequence (protein or nucleotide).

Annotation Detail Page

To view protein sequence annotations, go to Registry > Protein Sequences, and click a protein id in the Name column. Click the Sequence tab.

A somewhat simplified version of the annotations viewer is also used within the protein sequence registration wizard.

Graphical Representation

Clicking an annotation’s color bar highlights its description in the grid below, For example, if you click the green bar for sequence position 24-34, that annotation’s details are highlighted in the grid below, and vice versa.

Details Grid

The annotations details grid can be sorted by any of the available columns. The grid will always default to sorting the "Start" column in ascending order

Annotation Editor

The annotation editor has two tabs: Edit Annotation and Add Annotation. Adding or editing an annotation will refresh the grid and viewer to include your changes.

  • Note the asterisks marking required fields on the Add Annotation tab. The button at the bottom of the form will remain grayed out until all fields have been filled out.
  • The Type dropdown is pre-populated with the items in the List "AnnotationTypes".

In order to edit an annotation, select one from the grid or viewer and click the Edit Annotation tab.

Click the Edit button to enable the field inputs and action buttons:

  • Cancel: Cancels the edit.
  • Remove Annotation: Removes the annotation and deletes the details row from the grid.
  • Save: Save any changes to the selected annotation. The Save button will become enabled only when changes have been made to the form.

Controls

The controls in the bottom right panel let you customize the display region.

  • Index: Show or hide or show the position index numbers.
  • Annotations: Show or hide the annotation color bars.
  • Direction: Show or hide the direction indicator on the bars.

The sequence start and end points update to the currently selected annotation. The start and end points can be manually changed to any index values in the sequence, or can be reset to the full sequence by pressing the refresh button.

Clicking Copy sequence will copy the indicated segment to your clipboard for pasting (useful when registering a new protein sequence into the Registry).

Related Topics

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